Browse Skills

Guide users through creating Agent Skills for Claude Code. Use when the user wants to create, write, author, or design a new Skill, or needs help with SKILL.md files, frontmatter, or skill structure.

Batch-generate images via OpenAI Images API with random prompt sampler.

This skill should be used when the user asks to create an agent, add an agent, write a subagent, or needs guidance on agent structure, system prompts, triggering conditions.

This skill should be used when the user asks to create a slash command, add a command, write a custom command, define command arguments, or use command frontmatter.

This skill should be used when the user asks to create a hook, add a PreToolUse/PostToolUse/Stop hook, validate tool use, or implement prompt-based hooks.

This skill should be used when the user asks to add MCP server, integrate MCP, configure MCP in plugin, use .mcp.json, or set up Model Context Protocol.

This skill should be used when the user asks about plugin settings, store plugin configuration, user-configurable plugin, .local.md files, or plugin state files.

This skill should be used when the user asks to create a plugin, scaffold a plugin, understand plugin structure, organize plugin components, or set up plugin.json.

This skill should be used when the user wants to create a skill, add a skill to plugin, write a new skill, or needs guidance on skill structure and development best practices.

Migrate prompts and code from Claude Sonnet 4.0, Sonnet 4.5, or Opus 4.1 to Opus 4.5. Handles model string updates and prompt adjustments.

Guide for creating effective skills. This skill should be used when users want to create a new skill that extends Codex's capabilities with specialized knowledge, workflows, or tool integrations.

Applies Anthropic's official brand colors and typography to artifacts. Use when brand colors or style guidelines apply.

Comprehensive document creation, editing, and analysis with support for tracked changes, comments, formatting preservation, and text extraction.

A set of resources to help write internal communications like status reports, leadership updates, newsletters, FAQs, and incident reports.

Guide for creating high-quality MCP servers that enable LLMs to interact with external services through well-designed tools.

Suite of tools for creating elaborate, multi-component HTML artifacts using React, Tailwind CSS, and shadcn/ui.

Create distinctive, production-grade frontend interfaces with high design quality. Use this skill when the user asks to build web components, pages, or applications.

Toolkit for interacting with and testing local web applications using Playwright.

Comprehensive PDF manipulation toolkit for extracting text and tables, creating new PDFs, merging/splitting documents.

Comprehensive spreadsheet creation, editing, and analysis with support for formulas, formatting, data analysis.

Toolkit for styling artifacts with a theme. These artifacts can be slides, docs, reportings, HTML landing pages.

Guide users through a structured workflow for co-authoring documentation.

Creating algorithmic art using p5.js with seeded randomness and interactive parameter exploration.

Create beautiful visual art in .png and .pdf documents using design philosophy.

Knowledge and utilities for creating animated GIFs optimized for Slack.

description: "Presentation creation, editing, and analysis. When Claude needs to work with presentations (.pptx files) for: (1) Creating new presentations, (2) Modifying or editing content, (3) Working with layouts, (4) Adding comments or speaker notes, or any other presentation tasks"

Audit an Anthropic Cookbook notebook based on a rubric. Use whenever a notebook review or audit is requested.

Guides Claude in creating well-structured SKILL.md files following best practices. Provides clear guidelines for naming, structure, and content organization.

Use when starting any conversation - establishes how to find and use skills, requiring Skill tool invocation before ANY response.

Use when encountering any bug, test failure, or unexpected behavior, before proposing fixes.

Use when implementing complex logic that needs test coverage - write the test first, watch it fail.

name: brainstorming

name: dispatching-parallel-agents

name: executing-plans

name: finishing-a-development-branch

name: receiving-code-review

name: requesting-code-review

name: subagent-driven-development

name: using-git-worktrees

name: verification-before-completion

name: writing-plans

name: writing-skills

Create production-ready FastAPI projects with async patterns, dependency injection, and comprehensive error handling.

Master REST and GraphQL API design principles to build intuitive, scalable, and maintainable APIs.

Design LLM applications using the LangChain framework with agents, memory, and tool integration patterns.

Implement comprehensive evaluation strategies for LLM applications using automated metrics, human feedback, and benchmarking.

Master advanced prompt engineering techniques to maximize LLM performance, reliability, and controllability in production.

Build Retrieval-Augmented Generation (RAG) systems for LLM applications with vector databases and semantic search.

Build end-to-end MLOps pipelines from data preparation through model training, validation, and production deployment.

Transform data into compelling narratives using visualization, context, and persuasive structure.

Build production Apache Airflow DAGs with best practices for operators, sensors, testing, and deployment.

Select and optimize embedding models for semantic search and RAG applications.

Combine vector and keyword search for improved retrieval. Use when implementing RAG systems or building search engines.

Implement efficient similarity search with vector databases. Use when building semantic search or nearest neighbor queries.

Upgrade React applications to latest versions, migrate from class components to hooks, and adopt concurrent features.

Master Next.js 14+ App Router with Server Components, streaming, parallel routes, and advanced data fetching.

Build production React Native apps with Expo, navigation, native modules, offline sync, and cross-platform patterns.

Master modern React state management with Redux Toolkit, Zustand, Jotai, and React Query.

Build scalable design systems with Tailwind CSS, design tokens, component libraries, and responsive patterns.

Migrate from AngularJS to Angular using hybrid mode, incremental component rewriting, and dependency injection updates.

Master TypeScript's advanced type system including generics, conditional types, mapped types, template literals, and utility types.

Master ES6+ features including async/await, destructuring, spread operators, arrow functions, promises, modules.

Design multi-stage CI/CD pipelines with approval gates, security checks, and deployment orchestration.

Create production-ready GitHub Actions workflows for automated testing, building, and deploying applications.

Build GitLab CI/CD pipelines with multi-stage workflows, caching, and distributed runners for scalable automation.

Implement secure secrets management for CI/CD pipelines using Vault, AWS Secrets Manager, or native platform solutions.

Build reusable Terraform modules for AWS, Azure, and GCP infrastructure following infrastructure-as-code best practices.

Master effective code review practices to provide constructive feedback, catch bugs early, and foster knowledge sharing.

Master end-to-end testing with Playwright and Cypress to build reliable test suites that catch bugs.

Master monorepo management with Turborepo, Nx, and pnpm workspaces to build efficient, scalable multi-package repositories.

Manage major dependency version upgrades with compatibility analysis, staged rollout, and comprehensive testing.

Implement GitOps workflows with ArgoCD and Flux for automated, declarative Kubernetes deployments.

Design, organize, and manage Helm charts for templating and packaging Kubernetes applications.

Create production-ready Kubernetes manifests for Deployments, Services, ConfigMaps, and Secrets.

Set up Prometheus for comprehensive metric collection, storage, and monitoring of infrastructure and applications.

Configure Static Application Security Testing (SAST) tools for automated vulnerability detection in application code.

Master Bash Automated Testing System (Bats) for comprehensive shell script testing.

Automate changelog generation from commits, PRs, and releases following Keep a Changelog format.

Create structured incident response runbooks with step-by-step procedures, escalation paths, and recovery actions.

Optimize database queries, indexing strategies, and data modeling for high-performance applications.

Test Temporal workflows with pytest, time-skipping, and mocking strategies.

Build durable, fault-tolerant workflows using Temporal with Python SDK.

Test smart contracts using Hardhat and Foundry with unit tests, integration tests, and mainnet forking.

Build secure Solidity smart contracts following best practices for DeFi, NFTs, and DAOs.

Build robust web scraping solutions with BeautifulSoup, Scrapy, and request handling.

Implement comprehensive testing strategies with pytest, fixtures, mocking, and TDD.

Master asyncio, concurrent programming, and event loops for high-performance Python applications.

Design and implement GraphQL APIs with schema design, resolvers, and performance optimization.

Build high-performance gRPC services with protobuf, streaming, and load balancing.

Implement comprehensive testing strategies using Jest, Vitest, and Testing Library.

Create and manage production Grafana dashboards for real-time visualization of system and application metrics.

Implement Stripe payment processing for robust, PCI-compliant payment flows.

Build automated billing systems for recurring payments, invoicing, subscription lifecycle.

Master dbt (data build tool) for analytics engineering with model organization, testing, documentation.

Master authentication and authorization patterns including JWT, OAuth2, session management, and RBAC.

Implement Kubernetes security policies including NetworkPolicy, PodSecurityPolicy, and RBAC.

Configure mutual TLS (mTLS) for zero-trust service-to-service communication.

Implement GDPR-compliant data handling with consent management and data subject rights.

Master SQL query optimization, indexing strategies, and EXPLAIN analysis.

Execute database migrations with zero-downtime strategies and rollback procedures.

Design a PostgreSQL-specific schema. Covers best-practices, data types, indexing, constraints.

Generate and maintain OpenAPI 3.1 specifications from code, design-first specs, and validation patterns.

Comprehensive healthcare AI toolkit for developing, testing, and deploying machine learning models with clinical data. This skill should be used when working with electronic health records (EHR), clinical prediction tasks (mortality, readmission, drug recommendation), medical coding systems (ICD, ND

Generate or edit images using AI models (FLUX, Gemini). Use for general-purpose image generation including photos, illustrations, artwork, visual assets, concept art, and any image that isn't a technical diagram or schematic. For flowcharts, circuits, pathways, and technical diagrams, use the scient

Autonomous biomedical AI agent framework for executing complex research tasks across genomics, drug discovery, molecular biology, and clinical analysis. Use this skill when conducting multi-step biomedical research including CRISPR screening design, single-cell RNA-seq analysis, ADMET prediction, GW

Create publication-quality scientific diagrams using Nano Banana Pro AI with smart iterative refinement. Uses Gemini 3 Pro for quality review. Only regenerates if quality is below threshold for your document type. Specialized in neural network architectures, system diagrams, flowcharts, biological p

Cloud laboratory platform for automated protein testing and validation. Use when designing proteins and needing experimental validation including binding assays, expression testing, thermostability measurements, enzyme activity assays, or protein sequence optimization. Also use for submitting experi

This skill should be used for time series machine learning tasks including classification, regression, clustering, forecasting, anomaly detection, segmentation, and similarity search. Use when working with temporal data, sequential patterns, or time-indexed observations requiring specialized algorit

Access AlphaFold's 200M+ AI-predicted protein structures. Retrieve structures by UniProt ID, download PDB/mmCIF files, analyze confidence metrics (pLDDT, PAE), for drug discovery and structural biology.

This skill should be used when working with annotated data matrices in Python, particularly for single-cell genomics analysis, managing experimental measurements with metadata, or handling large-scale biological datasets. Use when tasks involve AnnData objects, h5ad files, single-cell RNA-seq data,

Infer gene regulatory networks (GRNs) from gene expression data using scalable algorithms (GRNBoost2, GENIE3). Use when analyzing transcriptomics data (bulk RNA-seq, single-cell RNA-seq) to identify transcription factor-target gene relationships and regulatory interactions. Supports distributed comp

Comprehensive Python library for astronomy and astrophysics. This skill should be used when working with astronomical data including celestial coordinates, physical units, FITS files, cosmological calculations, time systems, tables, world coordinate systems (WCS), and astronomical data analysis. Use

Benchling R&D platform integration. Access registry (DNA, proteins), inventory, ELN entries, workflows via API, build Benchling Apps, query Data Warehouse, for lab data management automation.

Primary Python toolkit for molecular biology. Preferred for Python-based PubMed/NCBI queries (Bio.Entrez), sequence manipulation, file parsing (FASTA, GenBank, FASTQ, PDB), advanced BLAST workflows, structures, phylogenetics. For quick BLAST, use gget. For direct REST API, use pubmed-database.

Efficient database search tool for bioRxiv preprint server. Use this skill when searching for life sciences preprints by keywords, authors, date ranges, or categories, retrieving paper metadata, downloading PDFs, or conducting literature reviews.

Primary Python tool for 40+ bioinformatics services. Preferred for multi-database workflows: UniProt, KEGG, ChEMBL, PubChem, Reactome, QuickGO. Unified API for queries, ID mapping, pathway analysis. For direct REST control, use individual database skills (uniprot-database, kegg-database).

Access BRENDA enzyme database via SOAP API. Retrieve kinetic parameters (Km, kcat), reaction equations, organism data, and substrate-specific enzyme information for biochemical research and metabolic pathway analysis.

Query CZ CELLxGENE Census (61M+ cells). Filter by cell type/tissue/disease, retrieve expression data, integrate with scanpy/PyTorch, for population-scale single-cell analysis.

Query ChEMBL's bioactive molecules and drug discovery data. Search compounds by structure/properties, retrieve bioactivity data (IC50, Ki), find inhibitors, perform SAR studies, for medicinal chemistry.

Quantum computing framework for building, simulating, optimizing, and executing quantum circuits. Use this skill when working with quantum algorithms, quantum circuit design, quantum simulation (noiseless or noisy), running on quantum hardware (Google, IonQ, AQT, Pasqal), circuit optimization and co

Comprehensive citation management for academic research. Search Google Scholar and PubMed for papers, extract accurate metadata, validate citations, and generate properly formatted BibTeX entries. This skill should be used when you need to find papers, verify citation information, convert DOIs to Bi

Generate professional clinical decision support (CDS) documents for pharmaceutical and clinical research settings, including patient cohort analyses (biomarker-stratified with outcomes) and treatment recommendation reports (evidence-based guidelines with decision algorithms). Supports GRADE evidence

Write comprehensive clinical reports including case reports (CARE guidelines), diagnostic reports (radiology/pathology/lab), clinical trial reports (ICH-E3, SAE, CSR), and patient documentation (SOAP, H&P, discharge summaries). Full support with templates, regulatory compliance (HIPAA, FDA, ICH-GCP)

Query ClinicalTrials.gov via API v2. Search trials by condition, drug, location, status, or phase. Retrieve trial details by NCT ID, export data, for clinical research and patient matching.

Access ClinPGx pharmacogenomics data (successor to PharmGKB). Query gene-drug interactions, CPIC guidelines, allele functions, for precision medicine and genotype-guided dosing decisions.

Query NCBI ClinVar for variant clinical significance. Search by gene/position, interpret pathogenicity classifications, access via E-utilities API or FTP, annotate VCFs, for genomic medicine.

Constraint-based metabolic modeling (COBRA). FBA, FVA, gene knockouts, flux sampling, SBML models, for systems biology and metabolic engineering analysis.

Access COSMIC cancer mutation database. Query somatic mutations, Cancer Gene Census, mutational signatures, gene fusions, for cancer research and precision oncology. Requires authentication.

Parallel/distributed computing. Scale pandas/NumPy beyond memory, parallel DataFrames/Arrays, multi-file processing, task graphs, for larger-than-RAM datasets and parallel workflows.

Work with Data Commons, a platform providing programmatic access to public statistical data from global sources. Use this skill when working with demographic data, economic indicators, health statistics, environmental data, or any public datasets available through Data Commons. Applicable for queryi

Pythonic wrapper around RDKit with simplified interface and sensible defaults. Preferred for standard drug discovery: SMILES parsing, standardization, descriptors, fingerprints, clustering, 3D conformers, parallel processing. Returns native rdkit.Chem.Mol objects. For advanced control or custom para

Molecular machine learning toolkit. Property prediction (ADMET, toxicity), GNNs (GCN, MPNN), MoleculeNet benchmarks, pretrained models, featurization, for drug discovery ML.

NGS analysis toolkit. BAM to bigWig conversion, QC (correlation, PCA, fingerprints), heatmaps/profiles (TSS, peaks), for ChIP-seq, RNA-seq, ATAC-seq visualization.

Multiagent AI system for scientific research assistance that automates research workflows from data analysis to publication. This skill should be used when generating research ideas from datasets, developing research methodologies, executing computational experiments, performing literature searches,

Diffusion-based molecular docking. Predict protein-ligand binding poses from PDB/SMILES, confidence scores, virtual screening, for structure-based drug design. Not for affinity prediction.

DNAnexus cloud genomics platform. Build apps/applets, manage data (upload/download), dxpy Python SDK, run workflows, FASTQ/BAM/VCF, for genomics pipeline development and execution.

Access and analyze comprehensive drug information from the DrugBank database including drug properties, interactions, targets, pathways, chemical structures, and pharmacology data. This skill should be used when working with pharmaceutical data, drug discovery research, pharmacology studies, drug-dr

Access European Nucleotide Archive via API/FTP. Retrieve DNA/RNA sequences, raw reads (FASTQ), genome assemblies by accession, for genomics and bioinformatics pipelines. Supports multiple formats.

Query Ensembl genome database REST API for 250+ species. Gene lookups, sequence retrieval, variant analysis, comparative genomics, orthologs, VEP predictions, for genomic research.

Comprehensive toolkit for protein language models including ESM3 (generative multimodal protein design across sequence, structure, and function) and ESM C (efficient protein embeddings and representations). Use this skill when working with protein sequences, structures, or function prediction; desig

Phylogenetic tree toolkit (ETE). Tree manipulation (Newick/NHX), evolutionary event detection, orthology/paralogy, NCBI taxonomy, visualization (PDF/SVG), for phylogenomics.

Perform comprehensive exploratory data analysis on scientific data files across 200+ file formats. This skill should be used when analyzing any scientific data file to understand its structure, content, quality, and characteristics. Automatically detects file type and generates detailed markdown rep

Query openFDA API for drugs, devices, adverse events, recalls, regulatory submissions (510k, PMA), substance identification (UNII), for FDA regulatory data analysis and safety research.

Parse FCS (Flow Cytometry Standard) files v2.0-3.1. Extract events as NumPy arrays, read metadata/channels, convert to CSV/DataFrame, for flow cytometry data preprocessing.

Framework for computational fluid dynamics simulations using Python. Use when running fluid dynamics simulations including Navier-Stokes equations (2D/3D), shallow water equations, stratified flows, or when analyzing turbulence, vortex dynamics, or geophysical flows. Provides pseudospectral methods

Query NCBI Gene via E-utilities/Datasets API. Search by symbol/ID, retrieve gene info (RefSeqs, GO, locations, phenotypes), batch lookups, for gene annotation and functional analysis.

This skill should be used when working with genomic interval data (BED files) for machine learning tasks. Use for training region embeddings (Region2Vec, BEDspace), single-cell ATAC-seq analysis (scEmbed), building consensus peaks (universes), or any ML-based analysis of genomic regions. Applies to

Access NCBI GEO for gene expression/genomics data. Search/download microarray and RNA-seq datasets (GSE, GSM, GPL), retrieve SOFT/Matrix files, for transcriptomics and expression analysis.

Python library for working with geospatial vector data including shapefiles, GeoJSON, and GeoPackage files. Use when working with geographic data for spatial analysis, geometric operations, coordinate transformations, spatial joins, overlay operations, choropleth mapping, or any task involving readi

This skill should be used at the start of any computationally intensive scientific task to detect and report available system resources (CPU cores, GPUs, memory, disk space). It creates a JSON file with resource information and strategic recommendations that inform computational approach decisions s

CLI/Python toolkit for rapid bioinformatics queries. Preferred for quick BLAST searches. Access to 20+ databases: gene info (Ensembl/UniProt), AlphaFold, ARCHS4, Enrichr, OpenTargets, COSMIC, genome downloads. For advanced BLAST/batch processing, use biopython. For multi-database integration, use bi

High-performance toolkit for genomic interval analysis in Rust with Python bindings. Use when working with genomic regions, BED files, coverage tracks, overlap detection, tokenization for ML models, or fragment analysis in computational genomics and machine learning applications.

Query NHGRI-EBI GWAS Catalog for SNP-trait associations. Search variants by rs ID, disease/trait, gene, retrieve p-values and summary statistics, for genetic epidemiology and polygenic risk scores.

Digital pathology image processing toolkit for whole slide images (WSI). Use this skill when working with histopathology slides, processing H&E or IHC stained tissue images, extracting tiles from gigapixel pathology images, detecting tissue regions, segmenting tissue masks, or preparing datasets for

Access Human Metabolome Database (220K+ metabolites). Search by name/ID/structure, retrieve chemical properties, biomarker data, NMR/MS spectra, pathways, for metabolomics and identification.

Automated hypothesis generation and testing using large language models. Use this skill when generating scientific hypotheses from datasets, combining literature insights with empirical data, testing hypotheses against observational data, or conducting systematic hypothesis exploration for research

Generate testable hypotheses. Formulate from observations, design experiments, explore competing explanations, develop predictions, propose mechanisms, for scientific inquiry across domains.

Comprehensive toolkit for preparing ISO 13485 certification documentation for medical device Quality Management Systems. Use when users need help with ISO 13485 QMS documentation, including (1) conducting gap analysis of existing documentation, (2) creating Quality Manuals, (3) developing required p

Direct REST API access to KEGG (academic use only). Pathway analysis, gene-pathway mapping, metabolic pathways, drug interactions, ID conversion. For Python workflows with multiple databases, prefer bioservices. Use this for direct HTTP/REST work or KEGG-specific control.

Electronic lab notebook API integration. Access notebooks, manage entries/attachments, backup notebooks, integrate with Protocols.io/Jupyter/REDCap, for programmatic ELN workflows.

This skill should be used when working with LaminDB, an open-source data framework for biology that makes data queryable, traceable, reproducible, and FAIR. Use when managing biological datasets (scRNA-seq, spatial, flow cytometry, etc.), tracking computational workflows, curating and validating dat

Latch platform for bioinformatics workflows. Build pipelines with Latch SDK, @workflow/@task decorators, deploy serverless workflows, LatchFile/LatchDir, Nextflow/Snakemake integration.

Create professional research posters in LaTeX using beamerposter, tikzposter, or baposter. Support for conference presentations, academic posters, and scientific communication. Includes layout design, color schemes, multi-column formats, figure integration, and poster-specific best practices for vis

Conduct comprehensive, systematic literature reviews using multiple academic databases (PubMed, arXiv, bioRxiv, Semantic Scholar, etc.). This skill should be used when conducting systematic literature reviews, meta-analyses, research synthesis, or comprehensive literature searches across biomedical,

Generate comprehensive market research reports (50+ pages) in the style of top consulting firms (McKinsey, BCG, Gartner). Features professional LaTeX formatting, extensive visual generation with scientific-schematics and generate-image, deep integration with research-lookup for data gathering, and m

Convert files and office documents to Markdown. Supports PDF, DOCX, PPTX, XLSX, images (with OCR), audio (with transcription), HTML, CSV, JSON, XML, ZIP, YouTube URLs, EPubs and more.

Mass spectrometry analysis. Process mzML/MGF/MSP, spectral similarity (cosine, modified cosine), metadata harmonization, compound ID, for metabolomics and MS data processing.

Foundational plotting library. Create line plots, scatter, bar, histograms, heatmaps, 3D, subplots, export PNG/PDF/SVG, for scientific visualization and publication figures.

Medicinal chemistry filters. Apply drug-likeness rules (Lipinski, Veber), PAINS filters, structural alerts, complexity metrics, for compound prioritization and library filtering.

Access NIH Metabolomics Workbench via REST API (4,200+ studies). Query metabolites, RefMet nomenclature, MS/NMR data, m/z searches, study metadata, for metabolomics and biomarker discovery.

Run Python code in the cloud with serverless containers, GPUs, and autoscaling. Use when deploying ML models, running batch processing jobs, scheduling compute-intensive tasks, or serving APIs that require GPU acceleration or dynamic scaling.

Molecular featurization for ML (100+ featurizers). ECFP, MACCS, descriptors, pretrained models (ChemBERTa), convert SMILES to features, for QSAR and molecular ML.

Comprehensive toolkit for creating, analyzing, and visualizing complex networks and graphs in Python. Use when working with network/graph data structures, analyzing relationships between entities, computing graph algorithms (shortest paths, centrality, clustering), detecting communities, generating

Comprehensive biosignal processing toolkit for analyzing physiological data including ECG, EEG, EDA, RSP, PPG, EMG, and EOG signals. Use this skill when processing cardiovascular signals, brain activity, electrodermal responses, respiratory patterns, muscle activity, or eye movements. Applicable for

Neuropixels neural recording analysis. Load SpikeGLX/OpenEphys data, preprocess, motion correction, Kilosort4 spike sorting, quality metrics, Allen/IBL curation, AI-assisted visual analysis, for Neuropixels 1.0/2.0 extracellular electrophysiology. Use when working with neural recordings, spike sorti

Microscopy data management platform. Access images via Python, retrieve datasets, analyze pixels, manage ROIs/annotations, batch processing, for high-content screening and microscopy workflows.

Query and analyze scholarly literature using the OpenAlex database. This skill should be used when searching for academic papers, analyzing research trends, finding works by authors or institutions, tracking citations, discovering open access publications, or conducting bibliometric analysis across

Query Open Targets Platform for target-disease associations, drug target discovery, tractability/safety data, genetics/omics evidence, known drugs, for therapeutic target identification.

Lab automation platform for Flex/OT-2 robots. Write Protocol API v2 protocols, liquid handling, hardware modules (heater-shaker, thermocycler), labware management, for automated pipetting workflows.

This skill should be used when converting academic papers into promotional and presentation formats including interactive websites (Paper2Web), presentation videos (Paper2Video), and conference posters (Paper2Poster). Use this skill for tasks involving paper dissemination, conference preparation, cr

Computational pathology toolkit for analyzing whole-slide images (WSI) and multiparametric imaging data. Use this skill when working with histopathology slides, H&E stained images, multiplex immunofluorescence (CODEX, Vectra), spatial proteomics, nucleus detection/segmentation, tissue graph construc

Access RCSB PDB for 3D protein/nucleic acid structures. Search by text/sequence/structure, download coordinates (PDB/mmCIF), retrieve metadata, for structural biology and drug discovery.

Systematic peer review toolkit. Evaluate methodology, statistics, design, reproducibility, ethics, figure integrity, reporting standards, for manuscript and grant review across disciplines.

Cross-platform Python library for quantum computing, quantum machine learning, and quantum chemistry. Enables building and training quantum circuits with automatic differentiation, seamless integration with PyTorch/JAX/TensorFlow, and device-independent execution across simulators and quantum hardwa

Perform AI-powered web searches with real-time information using Perplexity models via LiteLLM and OpenRouter. This skill should be used when conducting web searches for current information, finding recent scientific literature, getting grounded answers with source citations, or accessing informatio

Interactive scientific and statistical data visualization library for Python. Use when creating charts, plots, or visualizations including scatter plots, line charts, bar charts, heatmaps, 3D plots, geographic maps, statistical distributions, financial charts, and dashboards. Supports both quick vis

Fast DataFrame library (Apache Arrow). Select, filter, group_by, joins, lazy evaluation, CSV/Parquet I/O, expression API, for high-performance data analysis workflows.

Create professional research posters in LaTeX using beamerposter, tikzposter, or baposter. Support for conference presentations, academic posters, and scientific communication. Includes layout design, color schemes, multi-column formats, figure integration, and poster-specific best practices for vis

Integration with protocols.io API for managing scientific protocols. This skill should be used when working with protocols.io to search, create, update, or publish protocols; manage protocol steps and materials; handle discussions and comments; organize workspaces; upload and manage files; or integr

Query PubChem via PUG-REST API/PubChemPy (110M+ compounds). Search by name/CID/SMILES, retrieve properties, similarity/substructure searches, bioactivity, for cheminformatics.

Direct REST API access to PubMed. Advanced Boolean/MeSH queries, E-utilities API, batch processing, citation management. For Python workflows, prefer biopython (Bio.Entrez). Use this for direct HTTP/REST work or custom API implementations.

This skill should be used when working with reinforcement learning tasks including high-performance RL training, custom environment development, vectorized parallel simulation, multi-agent systems, or integration with existing RL environments (Gymnasium, PettingZoo, Atari, Procgen, etc.). Use this s

Differential gene expression analysis (Python DESeq2). Identify DE genes from bulk RNA-seq counts, Wald tests, FDR correction, volcano/MA plots, for RNA-seq analysis.

Python library for working with DICOM (Digital Imaging and Communications in Medicine) files. Use this skill when reading, writing, or modifying medical imaging data in DICOM format, extracting pixel data from medical images (CT, MRI, X-ray, ultrasound), anonymizing DICOM files, working with DICOM m

Laboratory automation toolkit for controlling liquid handlers, plate readers, pumps, heater shakers, incubators, centrifuges, and analytical equipment. Use this skill when automating laboratory workflows, programming liquid handling robots (Hamilton STAR, Opentrons OT-2, Tecan EVO), integrating lab

Materials science toolkit. Crystal structures (CIF, POSCAR), phase diagrams, band structure, DOS, Materials Project integration, format conversion, for computational materials science.

Bayesian modeling with PyMC. Build hierarchical models, MCMC (NUTS), variational inference, LOO/WAIC comparison, posterior checks, for probabilistic programming and inference.

Multi-objective optimization framework. NSGA-II, NSGA-III, MOEA/D, Pareto fronts, constraint handling, benchmarks (ZDT, DTLZ), for engineering design and optimization problems.

Python interface to OpenMS for mass spectrometry data analysis. Use for LC-MS/MS proteomics and metabolomics workflows including file handling (mzML, mzXML, mzTab, FASTA, pepXML, protXML, mzIdentML), signal processing, feature detection, peptide identification, and quantitative analysis. Apply when

Genomic file toolkit. Read/write SAM/BAM/CRAM alignments, VCF/BCF variants, FASTA/FASTQ sequences, extract regions, calculate coverage, for NGS data processing pipelines.

Therapeutics Data Commons. AI-ready drug discovery datasets (ADME, toxicity, DTI), benchmarks, scaffold splits, molecular oracles, for therapeutic ML and pharmacological prediction.

Deep learning framework (PyTorch Lightning). Organize PyTorch code into LightningModules, configure Trainers for multi-GPU/TPU, implement data pipelines, callbacks, logging (W&B, TensorBoard), distributed training (DDP, FSDP, DeepSpeed), for scalable neural network training.

Comprehensive quantum computing toolkit for building, optimizing, and executing quantum circuits. Use when working with quantum algorithms, simulations, or quantum hardware including (1) Building quantum circuits with gates and measurements, (2) Running quantum algorithms (VQE, QAOA, Grover), (3) Tr

Quantum mechanics simulations and analysis using QuTiP (Quantum Toolbox in Python). Use when working with quantum systems including: (1) quantum states (kets, bras, density matrices), (2) quantum operators and gates, (3) time evolution and dynamics (Schrödinger, master equations, Monte Carlo), (4) o

Cheminformatics toolkit for fine-grained molecular control. SMILES/SDF parsing, descriptors (MW, LogP, TPSA), fingerprints, substructure search, 2D/3D generation, similarity, reactions. For standard workflows with simpler interface, use datamol (wrapper around RDKit). Use rdkit for advanced control,

Query Reactome REST API for pathway analysis, enrichment, gene-pathway mapping, disease pathways, molecular interactions, expression analysis, for systems biology studies.

Write competitive research proposals for NSF, NIH, DOE, and DARPA. Agency-specific formatting, review criteria, budget preparation, broader impacts, significance statements, innovation narratives, and compliance with submission requirements.

Look up current research information using Perplexity's Sonar Pro Search or Sonar Reasoning Pro models through OpenRouter. Automatically selects the best model based on query complexity. Search academic papers, recent studies, technical documentation, and general research information with citations.

Single-cell RNA-seq analysis. Load .h5ad/10X data, QC, normalization, PCA/UMAP/t-SNE, Leiden clustering, marker genes, cell type annotation, trajectory, for scRNA-seq analysis.

Systematically evaluate scholarly work using the ScholarEval framework, providing structured assessment across research quality dimensions including problem formulation, methodology, analysis, and writing with quantitative scoring and actionable feedback.

Research ideation partner. Generate hypotheses, explore interdisciplinary connections, challenge assumptions, develop methodologies, identify research gaps, for creative scientific problem-solving.

Evaluate research rigor. Assess methodology, experimental design, statistical validity, biases, confounding, evidence quality (GRADE, Cochrane ROB), for critical analysis of scientific claims.

Build slide decks and presentations for research talks. Use this for making PowerPoint slides, conference presentations, seminar talks, research presentations, thesis defense slides, or any scientific talk. Provides slide structure, design templates, timing guidance, and visual validation. Works wit

Create publication figures with matplotlib/seaborn/plotly. Multi-panel layouts, error bars, significance markers, colorblind-safe, export PDF/EPS/TIFF, for journal-ready scientific plots.

Core skill for the deep research and writing tool. Write scientific manuscripts in full paragraphs (never bullet points). Use two-stage process: (1) create section outlines with key points using research-lookup, (2) convert to flowing prose. IMRAD structure, citations (APA/AMA/Vancouver), figures/ta

Biological data toolkit. Sequence analysis, alignments, phylogenetic trees, diversity metrics (alpha/beta, UniFrac), ordination (PCoA), PERMANOVA, FASTA/Newick I/O, for microbiome analysis.

Machine learning in Python with scikit-learn. Use when working with supervised learning (classification, regression), unsupervised learning (clustering, dimensionality reduction), model evaluation, hyperparameter tuning, preprocessing, or building ML pipelines. Provides comprehensive reference docum

Comprehensive toolkit for survival analysis and time-to-event modeling in Python using scikit-survival. Use this skill when working with censored survival data, performing time-to-event analysis, fitting Cox models, Random Survival Forests, Gradient Boosting models, or Survival SVMs, evaluating surv

This skill should be used when working with single-cell omics data analysis using scvi-tools, including scRNA-seq, scATAC-seq, CITE-seq, spatial transcriptomics, and other single-cell modalities. Use this skill for probabilistic modeling, batch correction, dimensionality reduction, differential expr

Statistical visualization. Scatter, box, violin, heatmaps, pair plots, regression, correlation matrices, KDE, faceted plots, for exploratory analysis and publication figures.

Model interpretability and explainability using SHAP (SHapley Additive exPlanations). Use this skill when explaining machine learning model predictions, computing feature importance, generating SHAP plots (waterfall, beeswarm, bar, scatter, force, heatmap), debugging models, analyzing model bias or

Process-based discrete-event simulation framework in Python. Use this skill when building simulations of systems with processes, queues, resources, and time-based events such as manufacturing systems, service operations, network traffic, logistics, or any system where entities interact with shared r

Use this skill for reinforcement learning tasks including training RL agents (PPO, SAC, DQN, TD3, DDPG, A2C, etc.), creating custom Gym environments, implementing callbacks for monitoring and control, using vectorized environments for parallel training, and integrating with deep RL workflows. This s

Statistical analysis toolkit. Hypothesis tests (t-test, ANOVA, chi-square), regression, correlation, Bayesian stats, power analysis, assumption checks, APA reporting, for academic research.

Statistical modeling toolkit. OLS, GLM, logistic, ARIMA, time series, hypothesis tests, diagnostics, AIC/BIC, for rigorous statistical inference and econometric analysis.

Query STRING API for protein-protein interactions (59M proteins, 20B interactions). Network analysis, GO/KEGG enrichment, interaction discovery, 5000+ species, for systems biology.

Use this skill when working with symbolic mathematics in Python. This skill should be used for symbolic computation tasks including solving equations algebraically, performing calculus operations (derivatives, integrals, limits), manipulating algebraic expressions, working with matrices symbolically

Graph Neural Networks (PyG). Node/graph classification, link prediction, GCN, GAT, GraphSAGE, heterogeneous graphs, molecular property prediction, for geometric deep learning.

Graph-based drug discovery toolkit. Molecular property prediction (ADMET), protein modeling, knowledge graph reasoning, molecular generation, retrosynthesis, GNNs (GIN, GAT, SchNet), 40+ datasets, for PyTorch-based ML on molecules, proteins, and biomedical graphs.

This skill should be used when working with pre-trained transformer models for natural language processing, computer vision, audio, or multimodal tasks. Use for text generation, classification, question answering, translation, summarization, image classification, object detection, speech recognition

Generate concise (3-4 page), focused medical treatment plans in LaTeX/PDF format for all clinical specialties. Supports general medical treatment, rehabilitation therapy, mental health care, chronic disease management, perioperative care, and pain management. Includes SMART goal frameworks, evidence

UMAP dimensionality reduction. Fast nonlinear manifold learning for 2D/3D visualization, clustering preprocessing (HDBSCAN), supervised/parametric UMAP, for high-dimensional data.

Direct REST API access to UniProt. Protein searches, FASTA retrieval, ID mapping, Swiss-Prot/TrEMBL. For Python workflows with multiple databases, prefer bioservices (unified interface to 40+ services). Use this for direct HTTP/REST work or UniProt-specific control.

Access USPTO APIs for patent/trademark searches, examination history (PEDS), assignments, citations, office actions, TSDR, for IP analysis and prior art searches.

Use this skill for processing and analyzing large tabular datasets (billions of rows) that exceed available RAM. Vaex excels at out-of-core DataFrame operations, lazy evaluation, fast aggregations, efficient visualization of big data, and machine learning on large datasets. Apply when users need to

Access comprehensive LaTeX templates, formatting requirements, and submission guidelines for major scientific publication venues (Nature, Science, PLOS, IEEE, ACM), academic conferences (NeurIPS, ICML, CVPR, CHI), research posters, and grant proposals (NSF, NIH, DOE, DARPA). This skill should be use

Chunked N-D arrays for cloud storage. Compressed arrays, parallel I/O, S3/GCS integration, NumPy/Dask/Xarray compatible, for large-scale scientific computing pipelines.

Access ZINC (230M+ purchasable compounds). Search by ZINC ID/SMILES, similarity searches, 3D-ready structures for docking, analog discovery, for virtual screening and drug discovery.

Create and manage Claude Code skills following Anthropic best practices. Covers skill structure, YAML frontmatter, and trigger patterns.

Suite of tools for creating elaborate, multi-component HTML artifacts using React, Tailwind CSS, and shadcn/ui.

Manage and trigger pre-built Zapier workflows and MCP tool orchestration for automations and research.

Assists in writing high-quality content by conducting research, adding citations, improving hooks, and iterating on outlines.

Comprehensive toolkit for developing with the CocoIndex library. Use when creating data transformation pipelines for AI data processing.

World-class prompt engineering skill for LLM optimization, prompt patterns, structured outputs, and AI product development.

UI design system toolkit for Senior UI Designer including design token generation, component documentation, responsive design calculations.

Comprehensive frontend development skill for building modern, performant web applications using ReactJS, NextJS, TypeScript, Tailwind CSS.

Frontend development guidelines for React/TypeScript applications. Modern patterns including Suspense, lazy loading, useSuspenseQuery.

TRPC with Tanstack Query patterns. Applies to files matching: *.tsx.

UI/UX design intelligence. 50 styles, 21 palettes, 50 font pairings, 20 charts, 8 stacks (React, Next.js, Vue, Svelte, SwiftUI, React Native, Flutter, Tailwind).

SEED React Headless component development specialist. Use when developing unstyled, logic-only components.

Create beautiful, accessible user interfaces with shadcn/ui components (built on Radix UI + Tailwind), Tailwind CSS utility-first styling.

Build modern full-stack web applications with Next.js (App Router, Server Components, RSC, PPR, SSR, SSG, ISR), Turborepo.

Create distinctive, high-converting landing pages that combine proven conversion elements with exceptional design quality.

Use when user wants to create a new Next.js 15 project (Todo/Blog/Dashboard/E-commerce/Custom domain) with App Router, ShadCN, Zustand, Tanstack Query.

DOM Testing Library patterns for behavior-driven UI testing. Framework-agnostic patterns for testing user interfaces.

React Testing Library patterns for testing React components, hooks, and context.

Comprehensive DevOps skill for CI/CD, infrastructure automation, containerization, and cloud platforms (AWS, GCP, Azure).

Comprehensive SecOps skill for application security, vulnerability management, compliance, and secure development practices.

Comprehensive QA and testing skill for quality assurance, test automation, and testing strategies for ReactJS, NextJS, NodeJS applications.

Comprehensive fullstack development skill for building complete web applications with React, Next.js, Node.js, GraphQL, and PostgreSQL.

Comprehensive GitHub project management with swarm-coordinated issue tracking, project board automation, and sprint planning.

Comprehensive GitHub release orchestration with AI swarm coordination for automated versioning, testing, deployment, and rollback management.

Advanced GitHub Actions workflow automation with AI swarm coordination, intelligent CI/CD pipelines, and comprehensive repository management.

AI-assisted pair programming with multiple modes (driver/navigator/switch), real-time verification, quality monitoring, and comprehensive testing.

Comprehensive backend development skill for building APIs, databases, and server-side applications.

Test authenticated routes using cookie-based authentication. Use when testing API endpoints.

Use when users need to debug, modify, or extend CLI commands, argument parsing, or CLI behavior.

Complete browser automation with Playwright. Auto-detects dev servers, writes clean test scripts.

Detect visual changes in UI components using screenshot comparison.

Automatically generate comprehensive unit tests from source code.

Execute integration tests validating component interactions and system integration.

Execute load testing, stress testing, and performance benchmarking.

Perform API fuzzing to discover edge cases, crashes, and security vulnerabilities.

Analyze code coverage metrics and identify untested code paths.

Execute chaos engineering experiments to test system resilience.

Use when working with Payload CMS projects (payload.config.ts, collections, fields, hooks, access control).

Write documentation following Metabase's conversational, clear, and user-focused style.

Extract text and tables from PDF files, fill forms, merge documents.

Draft professional emails for various contexts including business, technical, and customer communication.

Analyze Excel spreadsheets, create pivot tables, generate charts, and perform data analysis.

Identifies high-quality leads for your product or service by analyzing your business, searching for target companies.

Intelligently organizes your files and folders across your computer by understanding context.

Automatically organizes invoices and receipts for tax preparation by reading messy files.

Comprehensive security engineering skill for application security, penetration testing, security architecture.

Senior Information Security Manager specializing in ISO 27001 and ISO 27002 implementation.

Data privacy and regulatory compliance specialist for GDPR, CCPA, HIPAA.

Senior ISMS Audit Expert for internal and external information security management system auditing.

Audit access control implementations for security vulnerabilities and misconfigurations.

Scan for exposed secrets, API keys, and credentials in code.

Validate CSRF protection implementations for security gaps in web applications.

Automate security vulnerability testing covering OWASP Top 10, SQL injection, XSS, and CSRF.

Analyze HTTP security headers of web domains to identify vulnerabilities.

Compliance monitoring and validation with comprehensive guidance and automation.

Comprehensive PostgreSQL-specific table design reference covering data types, indexing, constraints.

Query performance analysis with comprehensive guidance and automation.

Schema migration management with comprehensive guidance and automation.

Horizontal sharding strategies with comprehensive guidance and automation.

Query performance analysis with comprehensive guidance and automation.

ORM model and code generation with comprehensive guidance and automation.

Automate database backup processes with scheduling and encryption.

Work with MongoDB (document database) and PostgreSQL (relational database).

PostgreSQL database documentation - SQL queries, database design, administration.

TimescaleDB - PostgreSQL extension for high-performance time-series analytics.

Use when querying Supabase, listing tables, getting schema, or working with RLS policies.

Database schema design, optimization, and migration patterns for PostgreSQL, MySQL, and NoSQL.

Review documentation changes for compliance with the Metabase writing style guide.

Personalized coding tutorials that build on your existing knowledge and use your actual codebase for examples.

Research libraries, APIs, and patterns using searchGitHub and Exa tools.

Reviews documentation for factual accuracy.

Consult official Claude Code documentation from docs.claude.com using selective fetching.

Rust documentation practices for HASH codebase.

Look up Microsoft API references, find working code samples, and verify SDK code is correct.

Automated documentation generation for databases.

Generate client SDKs in multiple languages from OpenAPI specifications.

Create comprehensive API documentation with examples, authentication guides, and SDKs.

Generate API contracts and OpenAPI specifications from code or design documents.

Searching internet for technical documentation using llms.txt standard, GitHub repositories via Repomix.

Create effective documentation that LLMs can discover and use.

Maintain project documentation synchronized with code.

Generate professional README.md files for projects.

Auto-generate API documentation from code and comments.

AI-powered comprehensive codebase documentation generator.

Generate and edit images using the Gemini API (Nano Banana Pro).